Negative Design for Protein Structural Uniqueness.
نویسندگان
چکیده
منابع مشابه
Identification of amino acids involved in protein structural uniqueness: implication for de novo protein design.
Structural uniqueness is characteristic of native proteins and is essential to express their biological functions. The major factors that bring about the uniqueness are specific interactions between hydrophobic residues and their unique packing in the protein core. To find the origin of the uniqueness in their amino acid sequences, we analyzed the distribution of the side chain rotational isome...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 1998
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.38.94